Fosinopril sodium
Functions and indications:
Used to treat hypertension and heart failure. When treating hypertension, it can be used alone as an initial treatment drug, or in combination with other antihypertensive drugs. When treating heart failure, it can be used in combination with diuretics.
Usage and dosage:
The dosage and dosage of different dosage forms and specifications of this product may vary. Please read the specific drug instructions for use, or follow the doctor’s advice. Fosinopril Sodium Tablets: Oral, the dosage should follow the principle of individualization. The usage and dosage for adults and children over 12 years old are as follows: 1. Hypertensive patients who are not treated with diuretics: The dosage range is 10-40 mg per day, a single dose, regardless of meals, and the normal initial dose for patients is 10 mg, once a day. After about four weeks, the dose is appropriately adjusted according to the blood pressure response. The dose exceeds 40 mg per day and does not enhance the antihypertensive effect. If blood pressure cannot be completely controlled by using it alone, a diuretic can be added. 2. Hypertensive patients who are also taking diuretics: Before starting this product, it is best to stop taking diuretics for a few days to reduce the risk of excessive blood pressure drop. If blood pressure cannot be adequately controlled after an observation period of approximately 4 weeks, diuretic treatment can be resumed. Another option is that if diuretics cannot be discontinued, close observation for several hours should be given when the initial dose of 10 mg of this product is given until blood pressure stabilizes. Hypertensive patients treated with diuretics can maintain average cerebral blood flow between 4 and 24 hours, although blood pressure is significantly reduced after taking this product. 3. Patients with heart failure: The recommended initial dose is 1 tablet (10 mg) once a day, with close medical monitoring. If the patient can tolerate it well, the dose can be gradually increased to 4 tablets (40 mg) once a day. Even if hypotension occurs after the initial dose, the dose should continue to be increased cautiously and the symptoms of hypotension should be effectively managed. This product should be used in combination with diuretics. 4. High-risk patients with heart failure: The following patients should start treatment in the hospital: patients with severe heart failure (NYHA IV grade); patients who are at special risk of hypotension with the first dose, such as patients receiving multiple or high-dose diuretics (such as >80mg furosemide), patients with reduced blood volume, hyponatremia, patients with hypotension (systolic blood pressure <90mmHg), and patients with unstable heart failure and receiving high-dose vasodilator treatment. 5. Elderly people and patients with impaired liver or kidney function do not need to reduce the dose.
Adverse reactions:
The dosage and usage of different dosage forms and specifications of this product may vary. Please read the specific drug instructions for use, or follow the doctor’s advice. Fosinopril Sodium Tablets: 1. The most common side effects of this product are dizziness, cough, upper respiratory tract symptoms, nausea or vomiting, diarrhea and abdominal pain, palpitations or chest pain, rash or itching, skeletal muscle pain or paresthesia, fatigue and taste disorders. 2. In trials for the treatment of heart failure, like other ACE inhibitors, it can cause hypotension, including orthostatic hypotension. Occasionally, pancreatitis has been reported in patients treated with ACE inhibitors, which has proven to be fatal in some cases. 3. The incidence and type of side effects do not differ between young and elderly patients. 4. Laboratory tests showed mild, temporary decreases in hemoglobin and red blood cell values, and occasional mild increases in blood urea nitrogen. For details on adverse reactions, please refer to the drug instructions.
Contraindications:
The usage and dosage of this product may vary in different dosage forms and specifications. Please read the specific drug instructions for use, or follow the doctor’s advice. Fosinopril Sodium Tablets: 1. For fosinopril, other ACE inhibitors (for example, in patients receiving other ACE inhibitors
