\u062a\u0645 \u062a\u0637\u0648\u064a\u0631 Kangyueda\u00ae (sepakinumab) \u0628\u0634\u0643\u0644 \u0645\u0633\u062a\u0642\u0644 \u0628\u0648\u0627\u0633\u0637\u0629 Conoya\u060c [3-4] \u0648\u0647\u0648 \u0623\u0648\u0644 \u062f\u0648\u0627\u0621 \u0645\u0636\u0627\u062f \u0644\u0640 IL-4R\u03b1 \u0645\u0639\u062a\u0645\u062f \u0644\u0644\u062a\u0633\u0648\u064a\u0642 \u0641\u064a \u0627\u0644\u0635\u064a\u0646 \u0648\u0627\u0644\u062b\u0627\u0646\u064a \u0641\u064a \u0627\u0644\u0639\u0627\u0644\u0645. [3-4]
\n\u064a\u0645\u0643\u0646 \u0644\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0645\u0646 Kangyueda\u00ae (sepakinumab) \u0623\u0646 \u062a\u062e\u0641\u0641 \u0628\u0633\u0631\u0639\u0629 \u0623\u0639\u0631\u0627\u0636 \u0627\u0644\u062d\u0643\u0629 \u0628\u0639\u062f \u064a\u0648\u0645 \u0648\u0627\u062d\u062f \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u061b \u0648\u0628\u0639\u062f \u0623\u0633\u0628\u0648\u0639\u064a\u0646 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u064a\u0643\u0648\u0646 \u0644\u0647\u0627 \u062a\u0623\u062b\u064a\u0631 \u062a\u062d\u0633\u0646 \u0642\u0648\u064a \u0639\u0644\u0649 \u0627\u0644\u0622\u0641\u0627\u062a \u0627\u0644\u062c\u0644\u062f\u064a\u0629 \u0641\u064a \u062c\u0645\u064a\u0639 \u0623\u062c\u0632\u0627\u0621 \u0627\u0644\u062c\u0633\u0645. [5] \u0628\u0639\u062f 52 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u062d\u0627\u062f\u064a\u060c \u064a\u0645\u0643\u0646 \u0644\u0640 Kangyueda\u00ae (sepakinumab) \u062a\u062d\u0642\u064a\u0642 \u0647\u062f\u0641 \u0627\u0644\u0639\u0644\u0627\u062c “\u0627\u0644\u0645\u0636\u0627\u0639\u0641 9 \u0627\u0644\u0642\u0627\u0628\u0644 \u0644\u0644\u0648\u0635\u0648\u0644” \u0644\u062a\u062d\u0633\u064a\u0646 \u0627\u0644\u0622\u0641\u0627\u062a \u0627\u0644\u062c\u0644\u062f\u064a\u0629 \u0628\u0634\u0643\u0644 \u0645\u0633\u062a\u062f\u0627\u0645 – \u0623\u064a \u0623\u0646 \u0623\u0643\u062b\u0631 \u0645\u0646 90% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u062d\u0642\u0642\u0648\u0627 \u062a\u062d\u0633\u0646\u064b\u0627 \u064a\u0632\u064a\u062f \u0639\u0646 75% \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0625\u0643\u0632\u064a\u0645\u0627 \u0648\u0645\u0624\u0634\u0631 \u0627\u0644\u0634\u062f\u0629 (EASI-75)\u060c \u0648\u062d\u0642\u0642 \u0645\u0627 \u064a\u0642\u0631\u0628 \u0645\u0646 80% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u062a\u062d\u0633\u0646\u064b\u0627 \u064a\u0632\u064a\u062f \u0639\u0646 90% \u0641\u064a \u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u0625\u0643\u0632\u064a\u0645\u0627 \u0648\u0645\u0624\u0634\u0631 \u0627\u0644\u0634\u062f\u0629 (EASI-90). [5] \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0642\u0644\u0644 Kangyueda\u00ae (sepakinumab) \u0628\u0634\u0643\u0644 \u0641\u0639\u0627\u0644 \u0645\u0646 \u062e\u0637\u0631 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0645\u0631\u0636 \u0648\u064a\u0638\u0647\u0631 \u0633\u0644\u0627\u0645\u0629 \u0648\u062a\u062d\u0645\u0644 \u062c\u064a\u062f\u064a\u0646. [5] \u064a\u0645\u0643\u0646 \u0644\u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0623\u0646 \u064a\u0642\u0644\u0644 \u0628\u0634\u0643\u0644 \u0641\u0639\u0627\u0644 \u0645\u0646 \u062e\u0637\u0631 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0645\u0631\u0636. \u0645\u0639\u062f\u0644 \u062a\u0643\u0631\u0627\u0631 \u0627\u0644\u0645\u0631\u0636 \u0647\u0648 0.9% \u0641\u0642\u0637 \u0628\u0639\u062f 52 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c \u06480.9% \u0641\u0642\u0637 \u0628\u0639\u062f 8 \u0623\u0633\u0627\u0628\u064a\u0639 \u0645\u0646 \u0627\u0644\u062a\u0648\u0642\u0641 \u0639\u0646 \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u062f\u0648\u0627\u0621. \u0645\u0639\u062f\u0644 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0644\u062a\u062d\u0645\u0629 \u0647\u0648 5.3% \u0641\u0642\u0637. [8]
\n\u062d\u0627\u0644\u064a\u064b\u0627\u060c \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0637\u0644\u0628 \u062a\u0631\u062e\u064a\u0635 \u062a\u0633\u0648\u064a\u0642 \u0633\u064a\u0628\u0627\u0643\u064a\u0646\u0648\u0645\u0627\u0628 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u0644\u062f \u0627\u0644\u062a\u0623\u062a\u0628\u064a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f \u0644\u062f\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0645\u0646 \u0642\u0628\u0644 \u0627\u0644\u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u0648\u0637\u0646\u064a\u0629 \u0644\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0637\u0628\u064a\u0629 \u0641\u064a 12 \u0633\u0628\u062a\u0645\u0628\u0631 2024 [6]\u060c \u0648\u062a\u0645 \u0642\u0628\u0648\u0644 \u0637\u0644\u0628 \u062a\u0631\u062e\u064a\u0635 \u062a\u0633\u0648\u064a\u0642\u0647 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u064a\u0648\u0628 \u0627\u0644\u0623\u0646\u0641\u064a\u0629 \u0627\u0644\u0645\u0632\u0645\u0646 \u0645\u0639 \u0627\u0644\u0632\u0648\u0627\u0626\u062f \u0627\u0644\u0623\u0646\u0641\u064a\u0629 [5] \u0648\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0646\u0641 \u0627\u0644\u062a\u062d\u0633\u0633\u064a \u0627\u0644\u0645\u0648\u0633\u0645\u064a [5]. [3]
\n\u0641\u064a 25 \u062f\u064a\u0633\u0645\u0628\u0631 2024\u060c \u062a\u0645 \u0648\u0635\u0641 \u0623\u0648\u0644 \u0639\u0627\u0645\u0644 \u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0645\u062d\u0644\u064a Kangyueda (\u062d\u0642\u0646\u0629 \u0633\u064a\u0628\u0627\u0643\u064a\u0646\u0648\u0645\u0627\u0628) \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u064a\u0648\u0628 \u0627\u0644\u0623\u0646\u0641\u064a\u0629 \u0627\u0644\u0645\u0632\u0645\u0646 \u0645\u0639 \u0627\u0644\u0632\u0648\u0627\u0626\u062f \u0627\u0644\u0623\u0646\u0641\u064a\u0629 \u0644\u0623\u0648\u0644 \u0645\u0631\u0629 \u0641\u064a \u0627\u0644\u0628\u0644\u0627\u062f \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u0649 \u0628\u0643\u064a\u0646 \u062a\u0648\u0646\u063a\u0631\u064a\u0646 \u0627\u0644\u062a\u0627\u0628\u0639 \u0644\u062c\u0627\u0645\u0639\u0629 \u0627\u0644\u0639\u0627\u0635\u0645\u0629 \u0627\u0644\u0637\u0628\u064a\u0629. [9]
\n\u0641\u064a 7 \u0641\u0628\u0631\u0627\u064a\u0631 2025\u060c \u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 \u0643\u0648\u0646\u0648\u064a\u0627 \u0639\u0646 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u062d\u0642\u0646\u0629 \u0633\u0628\u064a\u062a\u0648\u0628\u0627\u0632\u0648\u0645\u0627\u0628 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0646\u0641 \u0627\u0644\u062a\u062d\u0633\u0633\u064a \u0627\u0644\u0645\u0648\u0633\u0645\u064a. [14]
\n\u0645\u0648\u0627\u0635\u0641\u0629<\/p>\n
300 \u0645\u0644\u063a (2 \u0645\u0644) \/ \u0632\u062c\u0627\u062c\u0629 [2]
\n\u0645\u0643\u0648\u0646\u0627\u062a<\/p>\n
\u0627\u0644\u0645\u0627\u062f\u0629 \u0627\u0644\u0641\u0639\u0627\u0644\u0629: \u0633\u0643\u064a\u0628\u064a\u0632\u0648\u0645\u0627\u0628
\nSipuqibaimab \u0647\u0648 \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u0648\u062d\u064a\u062f \u0627\u0644\u0646\u0633\u064a\u0644\u0629 \u0645\u0628\u0634\u0631 (\u0646\u0648\u0639 IgG4) \u064a\u0633\u062a\u0647\u062f\u0641 \u0648\u062d\u062f\u0629 \u0645\u0633\u062a\u0642\u0628\u0644 \u0627\u0644\u0625\u0646\u062a\u0631\u0644\u0648\u0643\u064a\u0646 4 \u03b1 (IL-4R\u03b1) \u0627\u0644\u0645\u0639\u0628\u0631 \u0639\u0646\u0647\u0627 \u0641\u064a \u062e\u0644\u0627\u064a\u0627 \u0645\u0628\u064a\u0636 \u0627\u0644\u0647\u0627\u0645\u0633\u062a\u0631 \u0627\u0644\u0635\u064a\u0646\u064a \u0648\u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u062b\u0628\u0637 \u0625\u0634\u0627\u0631\u0627\u062a IL-4 \/ IL-13.
\n\u0627\u0644\u0645\u0648\u0627\u062f \u0627\u0644\u0645\u0633\u0627\u0639\u062f\u0629: \u0623\u0633\u064a\u062a\u0627\u062a \u0627\u0644\u0635\u0648\u062f\u064a\u0648\u0645\u060c \u062d\u0645\u0636 \u0627\u0644\u0623\u0633\u064a\u062a\u064a\u0643 \u0627\u0644\u062c\u0644\u064a\u062f\u064a\u060c \u0647\u064a\u062f\u0631\u0648\u0643\u0644\u0648\u0631\u064a\u062f \u0627\u0644\u0623\u0631\u062c\u064a\u0646\u064a\u0646\u060c \u0628\u0648\u0644\u064a\u0633\u0648\u0631\u0628\u0627\u062a 80 (II) \u0648\u0645\u0627\u0621 \u0644\u0644\u062d\u0642\u0646. [10]
\n\u0627\u0644\u062c\u0631\u0639\u0629<\/p>\n
\u064a\u062c\u0628 \u0623\u0646 \u064a\u0635\u0641 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0623\u062e\u0635\u0627\u0626\u064a \u0631\u0639\u0627\u064a\u0629 \u0635\u062d\u064a\u0629 \u0644\u062f\u064a\u0647 \u0627\u0644\u062e\u0628\u0631\u0629 \u0641\u064a \u062a\u0634\u062e\u064a\u0635 \u0648\u0639\u0644\u0627\u062c \u0627\u0644\u062d\u0627\u0644\u0629.
\n\u062c\u0631\u0639\u0629
\n\u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u064a\u0629 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0644\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0647\u064a 600 \u0645\u0644\u063a (300 \u0645\u0644\u063a \u064a\u062a\u0645 \u062d\u0642\u0646\u0647\u0627 \u0645\u0631\u062a\u064a\u0646)\u060c \u062a\u0644\u064a\u0647\u0627 \u062d\u0642\u0646\u0629 \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0628\u062c\u0631\u0639\u0629 300 \u0645\u0644\u063a \u0645\u0631\u0629 \u0643\u0644 \u0623\u0633\u0628\u0648\u0639\u064a\u0646.
\n\u064a\u062c\u0628 \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u0644\u062f \u0627\u0644\u062a\u0623\u062a\u0628\u064a \u0648\u0627\u0644\u0630\u064a\u0646 \u0644\u0627 \u064a\u0633\u062a\u062c\u064a\u0628\u0648\u0646 \u0644\u0647\u0630\u0627 \u0627\u0644\u062f\u0648\u0627\u0621 \u0628\u0639\u062f 16 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 \u0623\u0646 \u064a\u0641\u0643\u0631\u0648\u0627 \u0641\u064a \u0627\u0644\u062a\u0648\u0642\u0641 \u0639\u0646 \u0627\u0644\u0639\u0644\u0627\u062c. \u0642\u062f \u064a\u062a\u062d\u0633\u0646 \u0628\u0639\u0636 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0633\u062a\u062c\u064a\u0628\u0648\u0646 \u062c\u0632\u0626\u064a\u064b\u0627 \u0644\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0623\u0648\u0644\u064a \u0645\u0639 \u0627\u0644\u0627\u0633\u062a\u0645\u0631\u0627\u0631 \u0641\u064a \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0639\u062f 16 \u0623\u0633\u0628\u0648\u0639\u064b\u0627.
\n\u0627\u0644\u062c\u0631\u0639\u0629
\n\u064a\u0646\u0628\u063a\u064a \u062d\u0642\u0646 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0645\u0631\u0629 \u0643\u0644 \u0623\u0633\u0628\u0648\u0639\u064a\u0646. \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0645\u0643\u0627\u0646 \u0627\u0644\u062d\u0642\u0646 \u0641\u064a \u0627\u0644\u0628\u0637\u0646 \u0623\u0648 \u0627\u0644\u0641\u062e\u0630 \u0623\u0648 \u0627\u0644\u062c\u0632\u0621 \u0627\u0644\u0639\u0644\u0648\u064a \u0645\u0646 \u0627\u0644\u0630\u0631\u0627\u0639\u060c \u0628\u0627\u0633\u062a\u062b\u0646\u0627\u0621 \u0627\u0644\u0645\u0646\u0637\u0642\u0629 \u0627\u0644\u062a\u064a \u062a\u0642\u0639 \u0636\u0645\u0646 \u0646\u0637\u0627\u0642 5 \u0633\u0645 \u062d\u0648\u0644 \u0627\u0644\u0633\u0631\u0629.
\n\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u064a\u0629 600 \u0645\u0644\u063a\u060c \u064a\u062c\u0628 \u0625\u0639\u0637\u0627\u0621 \u062d\u0642\u0646\u062a\u064a\u0646 \u0645\u062a\u062a\u0627\u0644\u064a\u062a\u064a\u0646 \u0628\u062c\u0631\u0639\u0629 300 \u0645\u0644\u063a \u0641\u064a \u0645\u0648\u0627\u0642\u0639 \u062d\u0642\u0646 \u0645\u062e\u062a\u0644\u0641\u0629.
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\n\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0645\u0641\u0642\u0648\u062f
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\n\u0641\u0626\u0627\u062a \u062e\u0627\u0635\u0629
\n\u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0633\u0646\u064a\u0646 (\u226565 \u0633\u0646\u0629)
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\n\u0642\u0635\u0648\u0631 \u0643\u0644\u0648\u064a
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\n\u062a\u0644\u0641 \u0627\u0644\u0643\u0628\u062f
\n\u0644\u0627 \u062a\u0648\u062c\u062f \u0628\u064a\u0627\u0646\u0627\u062a \u0639\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u062e\u062a\u0644\u0627\u0644 \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0643\u0628\u062f. [10]
\n\u0627\u0644\u062d\u0631\u0643\u064a\u0629 \u0627\u0644\u062f\u0648\u0627\u0626\u064a\u0629
\n\u0625\u0630\u0627\u0639\u0629<\/p>\n
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\n\u0628\u0639\u062f \u0623\u0646 \u062a\u0644\u0642\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u0644\u062f \u0627\u0644\u062a\u0623\u062a\u0628\u064a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f \u062c\u0631\u0639\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629 \u0645\u0646 600 \u0645\u0644\u063a (\u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649) + 300 \u0645\u0644\u063a \u0643\u0644 \u0623\u0633\u0628\u0648\u0639\u064a\u0646 \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c\u060c \u0643\u0627\u0646 \u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u062f\u0648\u0627\u0621 \u0641\u064a \u0627\u0644\u062f\u0645 \u0642\u0631\u064a\u0628\u064b\u0627 \u0645\u0646 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0631\u0629 \u0639\u0646\u062f 12 \u0623\u0633\u0628\u0648\u0639\u064b\u0627\u060c \u0648\u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u062a\u0631\u0643\u064a\u0632\u0627\u062a \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0645\u0633\u062a\u0642\u0631\u0629 (\u00b1SD) \u0639\u0646\u062f 12 \u064816 \u0623\u0633\u0628\u0648\u0639\u064b\u0627 52.3 (\u00b122.8) \u064855.2 (\u00b125.5) \u0645\u064a\u0643\u0631\u0648\u062c\u0631\u0627\u0645\/\u0645\u0644\u060c \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a.
\n\u0645\u0648\u0632\u0639\u0629
\n\u0628\u0639\u062f \u062d\u0642\u0646\u0629 \u0648\u0627\u062d\u062f\u0629 \u062a\u062d\u062a \u0627\u0644\u062c\u0644\u062f \u0645\u0646 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c\u060c \u062a\u0631\u0627\u0648\u062d \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u062d\u062c\u0645 \u0627\u0644\u062a\u0648\u0632\u064a\u0639 \u0627\u0644\u0638\u0627\u0647\u0631\u064a \u0644\u0643\u0644 \u0645\u062c\u0645\u0648\u0639\u0629 \u062c\u0631\u0639\u0627\u062a (75 \u0645\u062c\u0645\u060c 150 \u0645\u062c\u0645\u060c 300 \u0645\u062c\u0645\u060c 600 \u0645\u062c\u0645) \u0645\u0646 3.64 \u0644\u062a\u0631 \u0625\u0644\u0649 6.73 \u0644\u062a\u0631\u060c \u0645\u0645\u0627 \u064a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0623\u0646 \u062a\u0648\u0632\u064a\u0639 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u064a\u0642\u062a\u0635\u0631 \u0628\u0634\u0643\u0644 \u0623\u0633\u0627\u0633\u064a \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 \u0627\u0644\u062f\u0648\u0631\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629.
\n\u0627\u0644\u062a\u062d\u0648\u0644 \u0627\u0644\u062d\u064a\u0648\u064a
\n\u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u0648\u062d\u064a\u062f \u0627\u0644\u0646\u0633\u064a\u0644\u0629 \u064a\u062a\u062d\u0644\u0644 \u0625\u0644\u0649 \u0628\u0628\u062a\u064a\u062f\u0627\u062a \u0635\u063a\u064a\u0631\u0629 \u0648\u0623\u062d\u0645\u0627\u0636 \u0623\u0645\u064a\u0646\u064a\u0629 \u0645\u0641\u0631\u062f\u0629 \u0641\u064a \u062c\u0633\u0645 \u0627\u0644\u0625\u0646\u0633\u0627\u0646.
\n\u0627\u0650\u0633\u0652\u062a\u064e\u0628\u0652\u0639\u064e\u062f
\n\u064a\u062d\u062a\u0648\u064a \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0639\u0644\u0649 \u0645\u0633\u0627\u0631\u064a\u0646 \u0631\u0626\u064a\u0633\u064a\u064a\u0646 \u0644\u0644\u0625\u0632\u0627\u0644\u0629: \u0627\u0644\u0625\u0632\u0627\u0644\u0629 \u0628\u0648\u0633\u0627\u0637\u0629 IL-4R\u03b1 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641\u0629 \u0648\u0627\u0644\u062a\u062d\u0644\u0644 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a. \u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u062f\u0627\u062e\u0644 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u062d\u064a \u0645\u0646\u062e\u0641\u0636\u064b\u0627\u060c \u064a\u0643\u0648\u0646 \u0627\u0644\u062a\u062e\u0644\u0635 \u0628\u0648\u0633\u0627\u0637\u0629 \u0627\u0644\u0647\u062f\u0641 IL-4R\u03b1 \u0647\u0648 \u0627\u0644\u0645\u0633\u064a\u0637\u0631\u061b \u0639\u0646\u062f\u0645\u0627 \u064a\u0643\u0648\u0646 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u062f\u0627\u062e\u0644 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u062d\u064a \u0645\u0631\u062a\u0641\u0639\u064b\u0627\u060c \u064a\u0643\u0648\u0646 \u0627\u0644\u062a\u062e\u0644\u0635 \u0627\u0644\u0628\u0631\u0648\u062a\u064a\u0646\u064a \u0647\u0648 \u0627\u0644\u0645\u0633\u064a\u0637\u0631. \u0628\u0639\u062f \u062c\u0631\u0639\u0627\u062a \u0645\u062a\u0639\u062f\u062f\u0629 \u0645\u0646 \u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0645\u0633\u062a\u0647\u062f\u0641\u0629 600 \u0645\u0644\u063a (\u0627\u0644\u062c\u0631\u0639\u0629 \u0627\u0644\u0623\u0648\u0644\u0649) + 300 \u0645\u0644\u063a \u0643\u0644 \u0623\u0633\u0628\u0648\u0639\u064a\u0646 \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u0644\u062f \u0627\u0644\u062a\u0623\u062a\u0628\u064a \u0627\u0644\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0625\u0644\u0649 \u0627\u0644\u0634\u062f\u064a\u062f\u060c \u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0627\u0644\u062a\u0635\u0641\u064a\u0629 \u0627\u0644\u0638\u0627\u0647\u0631\u064a\u0629 0.0246 \u0644\u062a\u0631\/\u0633\u0627\u0639\u0629 \u0648\u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0639\u0645\u0631 \u0627\u0644\u0646\u0635\u0641 \u0644\u0644\u0625\u0632\u0627\u0644\u0629 12.9 \u064a\u0648\u0645\u064b\u0627.
\n\u062e\u0637\u064a\/\u063a\u064a\u0631 \u062e\u0637\u064a
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\n\u0641\u0626\u0627\u062a \u062e\u0627\u0635\u0629
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\n\u0627\u062d\u062a\u064a\u0627\u0637\u0627\u062a<\/p>\n
\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0641\u0631\u0637 \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629
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\n\u0645\u0648\u0627\u0646\u0639 \u0627\u0644\u0627\u0633\u062a\u0639\u0645\u0627\u0644
\n\u0641\u064a \u062d\u0627\u0644\u0629 \u0639\u062f\u0645 \u0648\u062c\u0648\u062f \u062f\u0631\u0627\u0633\u0627\u062a \u0639\u062f\u0645 \u0627\u0644\u062a\u0648\u0627\u0641\u0642\u060c \u0644\u0627 \u064a\u062c\u0648\u0632 \u062e\u0644\u0637 \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0645\u0639 \u0623\u062f\u0648\u064a\u0629 \u0623\u062e\u0631\u0649. [10]<\/p>\n","protected":false},"excerpt":{"rendered":"
\u062a\u0645 \u062a\u0637\u0648\u064a\u0631 Kangyueda\u00ae (sepakinumab) \u0628\u0634\u0643\u0644 \u0645\u0633\u062a\u0642\u0644 …<\/p>\n","protected":false},"featured_media":12817,"template":"","meta":[],"etheme_brands":[],"product_cat":[91,94,79,74],"product_tag":[],"class_list":{"0":"post-12816","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-r-respiratory-system","7":"product_cat-s-sense-organ","8":"product_cat-skin-lymph","9":"product_cat-respiratory-skeleton-system","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/product\/12816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/types\/product"}],"version-history":[{"count":1,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/product\/12816\/revisions"}],"predecessor-version":[{"id":12818,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/product\/12816\/revisions\/12818"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=\/wp\/v2\/media\/12817"}],"wp:attachment":[{"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=12816"}],"wp:term":[{"taxonomy":"brand","embeddable":true,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fetheme_brands&post=12816"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=12816"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/tycoon-asia.com\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=12816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}