{"id":6008,"date":"2024-06-28T02:19:06","date_gmt":"2024-06-28T02:19:06","guid":{"rendered":"https:\/\/tycoon-asia.com\/?post_type=product&#038;p=6008"},"modified":"2024-07-04T04:34:49","modified_gmt":"2024-07-04T04:34:49","slug":"eribulin-mesylate-%e7%94%b2%e7%a3%ba%e9%85%b8%e8%89%be%e7%ab%8b%e5%b8%83%e6%9e%97","status":"publish","type":"product","link":"https:\/\/tycoon-asia.com\/?product=eribulin-mesylate-%e7%94%b2%e7%a3%ba%e9%85%b8%e8%89%be%e7%ab%8b%e5%b8%83%e6%9e%97","title":{"rendered":"\u062d\u0642\u0646 \u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a \u7532\u78fa\u9178\u827e\u7acb\u5e03\u6797"},"content":{"rendered":"<p>\u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u0627\u0648\u0644\u0649<br \/>\n\u062a\u0645 \u0625\u062c\u0631\u0627\u0621 \u0645\u0627 \u0645\u062c\u0645\u0648\u0639\u0647 \u062b\u0644\u0627\u062b \u062f\u0631\u0627\u0633\u0627\u062a \u0633\u0631\u064a\u0631\u064a\u0629 \u0641\u064a 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\u0627\u0644\u0639\u062f\u0644\u0627\u062a \u0641\u064a \u0627\u0644\u064a\u0648\u0645 15\u060c \u062a\u0645 \u062a\u0639\u062f\u064a\u0644 \u0627\u0644\u0646\u0638\u0627\u0645 \u0625\u0644\u0649 \u0627\u0644\u064a\u0648\u0645 \u0627\u0644\u0623\u0648\u0644\u060c \u0648\u0627\u0644\u062d\u0642\u0646 \u0641\u064a \u0627\u0644\u0648\u0631\u064a\u062f \u0641\u064a \u0627\u0644\u064a\u0648\u0645 \u0627\u0644\u062b\u0627\u0645\u0646\u060c \u0648\u062a\u0634\u0643\u0644 2 \u0644\u062a\u0631 \u064a\u0648\u0645\u064b\u0627 \u062f\u0648\u0631\u0629 \u0648\u0627\u062d\u062f\u0629. \u0645\u0646 \u0628\u064a\u0646 87 \u0645\u0631\u064a\u0636\u064b\u0627 \u064a\u0645\u0643\u0646 \u062a\u0642\u064a\u064a\u0645 \u0641\u0639\u0627\u0644\u064a\u062a\u0647\u0645\u060c \u0643\u0627\u0646 \u0644\u062f\u0649 10 (11.5%) \u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u062c\u0632\u0626\u064a\u0629 (PR)\u060c \u0648\u0643\u0627\u0646 37 (42.5%) \u0644\u062f\u064a\u0647\u0645 \u0645\u0631\u0636 \u0645\u0633\u062a\u0642\u0631 (SD)\u060c \u0648\u0643\u0627\u0646 37 (42.5%) \u0644\u062f\u064a\u0647\u0645 \u0645\u0631\u0636 \u062a\u062f\u0631\u064a\u062c\u064a (PD). )36 \u062d\u0627\u0644\u0629 (41.4%). \u0643\u0627\u0646 \u0645\u0639\u062f\u0644 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0645\u0648\u0636\u0648\u0639\u064a\u0629 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a (ORR) 11.5% (95% CI: 5.7% -20.1%)\u060c \u0648\u0643\u0627\u0646 \u0645\u0639\u062f\u0644 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 (PR + SD \u0639\u0644\u0649 \u0645\u062f\u0649 6 \u0623\u0634\u0647\u0631) 17.2% (95% CI: 10.0% -26.8%). . \u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0645\u062f\u0629 \u0627\u0644\u0627\u0633\u062a\u062c\u0627\u0628\u0629 (MDR) \u0648\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 \u0628\u062f\u0648\u0646 \u062a\u0642\u062f\u0645 (mPFS) \u0648\u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0627\u0644\u0628\u0642\u0627\u0621 \u0627\u0644\u0625\u062c\u0645\u0627\u0644\u064a (mOS) 171 \u064879 \u0648275 \u064a\u0648\u0645\u064b\u0627 \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a. \u0641\u064a \u0639\u0627\u0645 2010\u060c \u0643\u0648\u0631\u062a\u064a\u0633 \u0648\u0622\u062e\u0631\u0648\u0646. \u0630\u0643\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u064a\u0636\u064b\u0627 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0641\u062a\u0648\u062d\u0629 \u0627\u0644\u062a\u0633\u0645\u064a\u0629 \u0648\u0630\u0631\u0627\u0639 \u0648\u0627\u062d\u062f\u0629. \u062a\u0645 \u062a\u0633\u062c\u064a\u0644 \u0645\u0627 \u0645\u062c\u0645\u0648\u0639\u0647 299 \u0645\u0631\u064a\u0636\u0629 \u0645\u0635\u0627\u0628\u0629 \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0645\u062d\u0644\u064a\u064b\u0627 \u0648\u0627\u0644\u0630\u064a\u0646 \u0633\u0628\u0642 \u0623\u0646 \u062a\u0644\u0642\u0648\u0627 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0628\u0627\u0644\u0623\u0646\u062b\u0631\u0627\u0633\u064a\u0643\u0644\u064a\u0646 \u0648\u0627\u0644\u062a\u0627\u0643\u0633\u0627\u0646 \u0648\u0627\u0644\u0643\u0627\u0628\u064a\u0633\u064a\u062a\u0627\u0628\u064a\u0646 \u0641\u064a \u0627\u0644\u062f\u0631\u0627\u0633\u0629. \u0645\u0646 \u0628\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0623\u0648 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0646\u0642\u064a\u0644\u064a\u060c \u062a\u0644\u0642\u0649 291 \u0645\u0631\u064a\u0636\u064b\u0627 \u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a 1.4 \u0645\u0644\u063a\u0645\u060c \u062a\u0645 \u062d\u0642\u0646\u0647 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0648\u0631\u064a\u062f \u0644\u0645\u062f\u0629 2-5 \u062f\u0642\u0627\u0626\u0642\u060c \u0641\u064a \u0627\u0644\u0623\u064a\u0627\u0645 1 \u06488 \u064821 \u0643\u062f\u0648\u0631\u0629 \u0648\u0627\u062d\u062f\u0629. \u0645\u0646 \u0628\u064a\u0646 269 \u0645\u0631\u064a\u0636\u064b\u0627 \u064a\u0645\u0643\u0646 \u062a\u0642\u064a\u064a\u0645 \u0641\u0639\u0627\u0644\u064a\u062a\u0647\u0645\u060c \u062d\u0642\u0642 25 \u0645\u0631\u064a\u0636\u064b\u0627 (9.3%) PR\u060c \u0648125 \u0645\u0631\u064a\u0636\u064b\u0627 (46.5%) \u062d\u0642\u0642\u0648\u0627 SD\u060c \u0648116 \u0645\u0631\u064a\u0636\u064b\u0627 (43.1%) \u062d\u0642\u0642\u0648\u0627 PD. \u0643\u0627\u0646 ORR 9.3\u066a (95\u066a CI: 6.1\u066a -13.4\u066a)\u060c \u0648\u0643\u0627\u0646 \u0645\u0639\u062f\u0644 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 (PR + SD \u0639\u0644\u0649 \u0645\u062f\u0649 6 \u0623\u0634\u0647\u0631) 17.1\u066a. \u0643\u0627\u0646 MDR 4.1 \u0634\u0647\u0631\u064b\u0627\u060c \u0648\u0643\u0627\u0646 mPFS 2.6 \u0634\u0647\u0631\u064b\u0627\u060c \u0648\u0643\u0627\u0646 mOS 10.4 \u0634\u0647\u0631\u064b\u0627.<br \/>\n\u0641\u064a \u0639\u0627\u0645 2010\u060c \u0625\u064a\u0648\u0627\u062a\u0627 \u0648\u0622\u062e\u0631\u0648\u0646 \u0641\u064a \u0627\u0644\u064a\u0627\u0628\u0627\u0646. \u0630\u0643\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0645\u0646 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629. \u0643\u0627\u0646\u062a \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u064a\u0636\u064b\u0627 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u0641\u062a\u0648\u062d\u0629 \u0627\u0644\u062a\u0633\u0645\u064a\u0629 \u0648\u0630\u0631\u0627\u0639 \u0648\u0627\u062d\u062f\u0629. \u062a\u0644\u0642\u0649 80 \u0645\u0631\u064a\u0636\u064b\u0627 \u064a\u0645\u0643\u0646 \u062a\u0642\u064a\u064a\u0645\u0647\u0645 \u0645\u0635\u0627\u0628\u064a\u0646 \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0645\u062d\u0644\u064a\u064b\u0627 \u0623\u0648 \u0623\u0644\u0645 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0646\u0642\u064a\u0644\u064a \u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a. 1. 4 \u0645\u0644\u063a \u00b7 \u0645\u060c \u064a\u062a\u0645 \u062d\u0642\u0646\u0647 \u0641\u064a \u0627\u0644\u0648\u0631\u064a\u062f \u0644\u0645\u062f\u0629 2-5 \u062f\u0642\u0627\u0626\u0642\u060c \u062f \u0644\u062a\u0631\u060c 8 \u062f\u060c 21 \u062f \u0643\u062f\u0648\u0631\u0629 \u0648\u0627\u062d\u062f\u0629. \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0623\u0646 \u0645\u0639\u062f\u0644 ORR \u0643\u0627\u0646 21.3% (95% CI: 12.9% -31.8%)\u060c \u0648\u0643\u0627\u0646 \u0645\u0639\u062f\u0644 \u0645\u0639\u062f\u0644 \u0627\u0644\u0648\u0641\u064a\u0627\u062a 27.5% (95% CI: 18.1% -38.6%). \u0643\u0627\u0646 MDR 119 \u064a\u0648\u0645\u064b\u0627\u060c \u0648\u0643\u0627\u0646 mPFS 112 \u064a\u0648\u0645\u064b\u0627\u060c \u0648\u0643\u0627\u0646 mOS 331 \u064a\u0648\u0645\u064b\u0627.<br \/>\n\u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629<br \/>\n\u0627\u062b\u0646\u0627 \u0639\u0634\u0631 \u0648\u0622\u062e\u0631\u0648\u0646. \u0623\u0628\u0644\u063a\u062a \u0639\u0646 \u062f\u0631\u0627\u0633\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u062a\u0639\u062f\u062f\u0629 \u0627\u0644\u0645\u0631\u0627\u0643\u0632 \u0645\u062a\u0648\u0627\u0632\u064a\u0629 \u0648\u0645\u0636\u0628\u0648\u0637\u0629 \u0645\u0646 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 (\u062f\u0631\u0627\u0633\u0629 EMBRACE) \u062d\u064a\u062b \u062a\u0645 \u062a\u0642\u0633\u064a\u0645 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0645\u062a\u0642\u062f\u0645 \u0645\u062d\u0644\u064a\u064b\u0627 \u0623\u0648 \u0623\u0644\u0645 \u0627\u0644\u062b\u062f\u064a \u0627\u0644\u0646\u0642\u064a\u0644\u064a \u0628\u0634\u0643\u0644 \u0639\u0634\u0648\u0627\u0626\u064a \u0625\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0639\u0644\u0627\u062c \u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062a\u062d\u0643\u0645 (\u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0639\u0644\u0627\u062c \u0643\u064a\u0645\u064a\u0627\u0626\u064a \u0623\u062d\u0627\u062f\u064a \u0627\u0644\u0639\u0627\u0645\u0644 \u0622\u062e\u0631\u060c \u0639\u0644\u0627\u062c \u0627\u0644\u063a\u062f\u062f \u0627\u0644\u0635\u0645\u0627\u0621\u060c \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u060c \u0648\u0645\u0627 \u0625\u0644\u0649 \u0630\u0644\u0643)\u060c \u062a\u0645 \u062a\u0642\u0633\u064a\u0645 762 \u0645\u0631\u064a\u0636\u0627 \u0628\u0634\u0643\u0644 \u0639\u0634\u0648\u0627\u0626\u064a \u0625\u0644\u0649 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0648\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0645\u0631\u0627\u0642\u0628\u0629 \u0648\u0641\u0642\u0627 \u06442:1. \u062a\u0644\u0642\u062a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c (\u0646 = 508) \u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a 1.4 \u0645\u0644\u063a \u00b7 \u0645\u060c 2-5 \u062f\u0642\u0627\u0626\u0642 \u0644\u0644\u062d\u0642\u0646 \u0641\u064a \u0627\u0644\u0648\u0631\u064a\u062f\u060c \u062f 1\u060c \u062f 8\u060c \u0648 21 \u062f \u062a\u0634\u0643\u0644 \u062f\u0648\u0631\u0629. \u062a\u0644\u0642\u062a \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0636\u0627\u0628\u0637\u0629 (\u0646 = 254) \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0642\u0644\u064a\u062f\u064a\u060c \u0648\u062a\u0644\u0642\u0649 96\u066a \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0626\u064a\u060c \u0648\u062a\u0644\u0642\u0649 4\u066a \u0639\u0644\u0627\u062c \u0627\u0644\u063a\u062f\u062f \u0627\u0644\u0635\u0645\u0627\u0621. \u0648\u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0646 \u0625\u062c\u0645\u0627\u0644\u064a \u0641\u062a\u0631\u0629 \u0627\u0644\u0628\u0642\u0627\u0621 \u0639\u0644\u0649 \u0642\u064a\u062f \u0627\u0644\u062d\u064a\u0627\u0629 \u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0639\u0644\u0627\u062c \u0628\u0627\u0644\u0625\u0631\u0628\u064a\u0648\u0644\u064a\u0646 \u0645\u064a\u0633\u064a\u0644\u0627\u062a \u0643\u0627\u0646 13.1 \u0634\u0647\u0631\u064b\u0627\u060c \u0648\u0643\u0627\u0646 \u0625\u062c\u0645\u0627\u0644\u064a \u0648\u0642\u062a \u0627\u0644\u0628\u0642\u0627\u0621 \u0644\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0636\u0627\u0628\u0637\u0629 10.6 \u0634\u0647\u0631\u064b\u0627. \u0643\u0627\u0646 \u0647\u0646\u0627\u0643 \u0641\u0631\u0642 \u0630\u0648 \u062f\u0644\u0627\u0644\u0629 \u0625\u062d\u0635\u0627\u0626\u064a\u0629 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