{"id":9361,"date":"2024-06-28T02:56:19","date_gmt":"2024-06-28T02:56:19","guid":{"rendered":"https:\/\/tycoon-asia.com\/?post_type=product&#038;p=9361"},"modified":"2024-07-02T02:52:11","modified_gmt":"2024-07-02T02:52:11","slug":"ripretinib-tablets","status":"publish","type":"product","link":"https:\/\/tycoon-asia.com\/?product=ripretinib-tablets","title":{"rendered":"\u0623\u0642\u0631\u0627\u0635 \u0631\u064a\u0628\u0631\u064a\u062a\u064a\u0646\u064a\u0628"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"<p>\u0627\u0644\u0648\u0638\u064a\u0641\u0629 \u0648\u0627\u0644\u062f\u0644\u0627\u0644\u0629: \u0647\u0630\u0627 \u0627\u0644\u0645\u0646\u062a\u062c \u0645\u0646\u0627\u0633\u0628 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0628\u0627\u0644\u063a\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0623\u0648\u0631\u0627\u0645 \u0627\u0646\u0633\u062c\u0629 \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629 (GIST) \u0648\u0627\u0644\u0630\u064a\u0646 \u062a\u0644\u0642\u0648\u0627 \u0633\u0627\u0628\u0642\u064b\u0627 3 \u0623\u0648 \u0623\u0643\u062b\u0631 \u0645\u0646 \u0645\u062b\u0628\u0637\u0627\u062a \u0627\u0644\u062a\u064a\u0631\u0648\u0632\u064a\u0646 \u0643\u064a\u0646\u0627\u0632 (\u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0625\u064a\u0645\u0627\u062a\u064a\u0646\u064a\u0628). \u062a\u0645\u062a \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0645\u0624\u0634\u0631 \u0628\u0634\u0643\u0644 \u0645\u0634\u0631\u0648\u0637 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 GISTINVICTUS \u0627\u0644\u0645\u0643\u0648\u0646\u0629 \u0645\u0646 4 \u0623\u0633\u0637\u0631. \u0633\u062a\u0639\u062a\u0645\u062f \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u0643\u0627\u0645\u0644\u0629 \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u0645\u0624\u0634\u0631 \u0639\u0644\u0649 \u0627\u0644\u0641\u0627\u0626\u062f\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0644\u062a\u062c\u0631\u0628\u0629 ZL-2307-002 \u0627\u0644\u062c\u0627\u0631\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0635\u064a\u0646\u064a\u064a\u0646. 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\u0627\u0644\u0630\u064a\u0646 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0622\u0644\u0627\u0645 \u0627\u0644\u0628\u0637\u0646 (4.7%)\u060c \u0648\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 (3.5%)\u060c \u0648\u0627\u0644\u063a\u062b\u064a\u0627\u0646 (2.4%)\u060c \u0648\u0627\u0644\u0642\u064a\u0621 (2.4%). \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0629 \u0627\u0644\u062a\u064a \u0623\u062f\u062a \u0625\u0644\u0649 \u0627\u0644\u062a\u0648\u0642\u0641 \u0627\u0644\u062f\u0627\u0626\u0645 \u0644\u0644\u0639\u0644\u0627\u062c \u0641\u064a 8\u066a \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628 (\u0646\u0633\u0628\u0629 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u22651\u066a) \u0634\u0645\u0644\u062a \u062a\u062f\u0647\u0648\u0631 \u0627\u0644\u062d\u0627\u0644\u0629 \u0627\u0644\u0639\u0627\u0645\u0629 (2.4\u066a)\u060c \u0648\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 (1.2\u066a)\u060c \u0648\u0641\u0634\u0644 \u0627\u0644\u0642\u0644\u0628 (1.2\u066a)\u060c \u0648PPES (1.2\u066a). ) \u0648\u0627\u0644\u0642\u064a\u0621 (1.2\u066a). \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0629 \u0627\u0644\u062a\u064a \u0623\u062f\u062a \u0625\u0644\u0649 \u0648\u0642\u0641 \u0627\u0644\u0639\u0644\u0627\u062c \u0641\u064a 24\u066a \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628 (\u0645\u0639\u062f\u0644 \u0627\u0644\u0625\u0635\u0627\u0628\u0629&gt; 2\u066a) \u0634\u0645\u0644\u062a \u0627\u0644\u063a\u062b\u064a\u0627\u0646 (3.5\u066a)\u060c \u0648\u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0628\u064a\u0644\u064a\u0631\u0648\u0628\u064a\u0646 \u0641\u064a \u0627\u0644\u062f\u0645 (2.4\u066a)\u060c \u0648PPES (2.4\u066a). \u062d\u062f\u062b\u062a \u062a\u062e\u0641\u064a\u0636\u0627\u062a \u0641\u064a \u0627\u0644\u062c\u0631\u0639\u0629 \u0628\u0633\u0628\u0628 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0629 \u0641\u064a 7\u066a \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628. \u0648\u0634\u0645\u0644\u062a \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0629 \u0627\u0644\u062a\u064a \u0623\u062f\u062a \u0625\u0644\u0649 \u062a\u062e\u0641\u064a\u0636 \u0627\u0644\u062c\u0631\u0639\u0629 (\u0646\u0633\u0628\u0629 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u22651.2\u066a) \u0622\u0644\u0627\u0645 \u0627\u0644\u0628\u0637\u0646\u060c \u0648\u0627\u0644\u0625\u062b\u0627\u0631\u0629\u060c \u0648\u0627\u0644\u062b\u0639\u0644\u0628\u0629\u060c \u0648\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0645\u0641\u0627\u0635\u0644\u060c \u0648\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u062c\u0644\u062f\u060c \u0648\u0627\u0636\u0637\u0631\u0627\u0628\u0627\u062a \u0627\u0644\u062c\u0647\u0627\u0632 \u0627\u0644\u0647\u0636\u0645\u064a\u060c \u0648\u0641\u0631\u0637 \u0627\u0644\u062d\u0633\u0627\u0633\u064a\u0629\u060c \u0648\u0623\u0644\u0645 \u0639\u0636\u0644\u064a\u060c \u0648PPES\u060c \u0648\u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0648\u0632\u0646. \u0643\u0627\u0646\u062a \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0634\u064a\u0648\u0639\u064b\u0627 (\u226520\u066a) \u0647\u064a \u0627\u0644\u062b\u0639\u0644\u0628\u0629 \u0648\u0627\u0644\u062a\u0639\u0628 \u0648\u0627\u0644\u063a\u062b\u064a\u0627\u0646 \u0648\u0622\u0644\u0627\u0645 \u0627\u0644\u0628\u0637\u0646 \u0648\u0627\u0644\u0625\u0645\u0633\u0627\u0643 \u0648\u0623\u0644\u0645 \u0639\u0636\u0644\u064a \u0648\u0627\u0644\u0625\u0633\u0647\u0627\u0644 \u0648\u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0634\u0647\u064a\u0629 \u0648PPES \u0648\u0627\u0644\u0642\u064a\u0621. \u0643\u0627\u0646\u062a \u0627\u0644\u062a\u0634\u0648\u0647\u0627\u062a \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a\u0629 \u0627\u0644\u0623\u0643\u062b\u0631 \u0634\u064a\u0648\u0639\u064b\u0627 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 3 \u0623\u0648 4 (\u22654\u066a) \u0647\u064a \u0632\u064a\u0627\u062f\u0629 \u0627\u0644\u0644\u064a\u0628\u0627\u0632 \u0641\u064a \u0627\u0644\u0645\u0635\u0644 \u0648\u0627\u0646\u062e\u0641\u0627\u0636 \u0641\u0648\u0633\u0641\u0627\u062a \u0627\u0644\u0645\u0635\u0644. \u064a\u0644\u062e\u0635 \u0627\u0644\u062c\u062f\u0648\u0644\u0627\u0646 2 \u06483 \u0623\u062f\u0646\u0627\u0647 \u0627\u0644\u062a\u0641\u0627\u0639\u0644\u0627\u062a \u0627\u0644\u0636\u0627\u0631\u0629 \u0648\u0627\u0644\u062a\u0634\u0648\u0647\u0627\u062a \u0627\u0644\u0645\u062e\u0628\u0631\u064a\u0629 \u0627\u0644\u0647\u0627\u0645\u0629 \u0627\u0644\u062a\u064a \u062d\u062f\u062b\u062a \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a. \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062e\u0644\u0644 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062d\u0645\u0631 \u0627\u0644\u0631\u0627\u062d\u064a\u0629 \u0627\u0644\u0623\u062e\u0645\u0635\u064a\u0629 \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0639\u0627\u0646\u0649 21\u066a \u0645\u0646 85 \u0645\u0631\u064a\u0636\u064b\u0627 \u062a\u0645 \u0639\u0644\u0627\u062c\u0647\u0645 \u0628\u062f\u0648\u0627\u0621 \u0631\u064a\u0628\u0631\u064a\u062a\u064a\u0646\u064a\u0628 \u0645\u0646 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u062d\u0644\u0644 \u0627\u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062d\u0645\u0631 \u0627\u0644\u0631\u0627\u062d\u064a\u0629 \u0627\u0644\u0623\u062e\u0645\u0635\u064a\u0629 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 1-2 (PPES). \u0623\u062f\u0649 PPES \u0625\u0644\u0649 \u0627\u0644\u062a\u0648\u0642\u0641 \u0627\u0644\u062f\u0627\u0626\u0645 \u0644\u0644\u0639\u0644\u0627\u062c \u0644\u062f\u0649 1.2% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u0648\u062a\u0639\u0644\u064a\u0642 \u0627\u0644\u0639\u0644\u0627\u062c \u0644\u062f\u0649 2.4% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649\u060c \u0648\u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u062c\u0631\u0639\u0629 \u0644\u062f\u0649 1.2% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649. \u0623\u0648\u0631\u0627\u0645 \u062c\u0644\u062f\u064a\u0629 \u0623\u0648\u0644\u064a\u0629 \u062c\u062f\u064a\u062f\u0629 \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0623\u0635\u064a\u0628 4.7% \u0645\u0646 85 \u0645\u0631\u064a\u0636\u064b\u0627 \u062a\u0645 \u0639\u0644\u0627\u062c\u0647\u0645 \u0628\u062f\u0648\u0627\u0621 &#8220;\u0631\u064a\u0628\u0631\u064a\u0646\u062a\u064a\u0646\u064a\u0628&#8221; \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062d\u0631\u0634\u0641\u064a\u0629 \u0627\u0644\u062c\u0644\u062f\u064a\u0629 (cuSCC)\u060c \u0645\u0639 \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0648\u0642\u062a \u062d\u062f\u0648\u062b \u0647\u0630\u0627 \u0627\u0644\u062d\u062f\u062b \u0644\u0623\u0648\u0644 \u0645\u0631\u0629 \u0648\u0647\u0648 4.6 \u0623\u0634\u0647\u0631 (\u0627\u0644\u0645\u062f\u0649: 3.8-6 \u0623\u0634\u0647\u0631). \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0645\u062c\u0645\u0639\u0629\u060c \u062d\u062f\u062b \u0627\u0644\u0648\u0631\u0645 \u0627\u0644\u0634\u0627\u0626\u0643\u064a cuSCC \u0648\u0627\u0644\u0648\u0631\u0645 \u0627\u0644\u0634\u0627\u0626\u0643\u064a \u0627\u0644\u0642\u0631\u0646\u064a \u0641\u064a 7\u066a \u06481.9\u066a \u0645\u0646 351 \u0645\u0631\u064a\u0636\u064b\u0627\u060c \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a. \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0623\u0635\u064a\u0628 2.4% \u0645\u0646 85 \u0645\u0631\u064a\u0636\u064b\u0627 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u062f\u0648\u0627\u0621 ripretinib \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062c\u0644\u062f. \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0645\u062c\u0645\u0639\u0629\u060c \u0623\u0635\u064a\u0628 0.9% \u0645\u0646 351 \u0645\u0631\u064a\u0636\u064b\u0627 \u0628\u0633\u0631\u0637\u0627\u0646 \u0627\u0644\u062c\u0644\u062f. \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0623\u0635\u064a\u0628 14% \u0645\u0646 85 \u0645\u0631\u064a\u0636\u0627\u064b \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628 \u0628\u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 1-3\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0631\u062a\u0641\u0627\u0639 \u0636\u063a\u0637 \u0627\u0644\u062f\u0645 \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 3 \u0641\u064a 7% \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649. \u062e\u0644\u0644 \u0641\u064a \u0648\u0638\u0627\u0626\u0641 \u0627\u0644\u0642\u0644\u0628: \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c \u0623\u0635\u064a\u0628 1.2% \u0645\u0646 85 \u0645\u0631\u064a\u0636\u064b\u0627 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0644\u0631\u064a\u0628\u064a\u062a\u064a\u0646\u064a\u0628 \u0628\u0642\u0635\u0648\u0631 \u0641\u064a \u0627\u0644\u0642\u0644\u0628. \u0641\u064a \u062f\u0631\u0627\u0633\u0629 INVICTUS\u060c 2.6% \u0645\u0646 77 \u0645\u0631\u064a\u0636\u064b\u0627 \u0639\u0648\u0644\u062c\u0648\u0627 \u0628\u0627\u0633\u062a\u062e\u062f\u0627\u0645 Ripretinib \u0648\u0627\u0644\u0630\u064a\u0646 \u0644\u062f\u064a\u0647\u0645 \u0645\u062e\u0637\u0637 \u0635\u062f\u0649 \u0627\u0644\u0642\u0644\u0628 \u0645\u0631\u0629 \u0648\u0627\u062d\u062f\u0629 \u0639\u0644\u0649 \u0627\u0644\u0623\u0642\u0644 \u0639\u0646\u062f \u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633 \u0648\u0628\u0639\u062f \u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633 \u0639\u0627\u0646\u0648\u0627 \u0645\u0646 \u0627\u0646\u062e\u0641\u0627\u0636 \u0627\u0644\u0643\u0633\u0631 \u0627\u0644\u0642\u0630\u0641\u064a \u0645\u0646 \u0627\u0644\u062f\u0631\u062c\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629. \u0641\u064a \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0633\u0644\u0627\u0645\u0629 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\u062d\u062f\u0648\u062b 1.1%\u060c \u0645\u0646\u0647\u0627 \u0627\u0644\u0633\u0643\u062a\u0629 \u0627\u0644\u0642\u0644\u0628\u064a\u0629. \u0648\u0627\u062d\u062a\u0634\u0627\u0621 \u0639\u0636\u0644\u0629 \u0627\u0644\u0642\u0644\u0628 \u0623\u062f\u0649 \u0643\u0644 \u0645\u0646\u0647\u0645\u0627 \u0625\u0644\u0649 \u0648\u0641\u0627\u0629 \u0645\u0631\u064a\u0636 \u0648\u0627\u062d\u062f.<br \/>\n\u0645\u0648\u0627\u0646\u0639 \u0627\u0644\u0627\u0633\u062a\u0639\u0645\u0627\u0644:<br \/>\n\u0644\u0627 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