Effects and efficacy:
Apixaban is suitable for adult patients undergoing elective hip or knee replacement surgery to prevent venous thromboembolic events (VTE).
Usage and dosage:
The recommended dose of this product is 2.5 mg each time, taken orally twice a day, with water, and is not affected by meals. The first dose should be between 12 and 24 hours after surgery. When deciding the specific time point for taking the medicine in this time window, the doctor needs to consider both the potential benefits of early anticoagulation to prevent VTE and the risk of postoperative bleeding. For patients undergoing hip replacement: the recommended course of treatment is 32 to 38 days. For patients undergoing knee replacement: the recommended course of treatment is 10 to 14 days. If a dose is missed, the patient should take this product immediately and then continue to take the medicine twice a day. When switching from injectable anticoagulants to this product for treatment, it can be started from the next dosing time (and vice versa). If the patient cannot swallow the whole tablet, the product can be crushed and suspended in water or 5% glucose solution, or apple juice, or mixed with applesauce and taken orally in time. Alternatively, crush the product, suspend it in 60 ml of water or 5% glucose solution, and administer it promptly through a nasogastric tube. The crushed product is stable in water, 5% glucose solution, apple juice, and applesauce within 4 hours.
Drug contraindications:
Contraindicated if allergic to this product
Related dosage forms:
Tablets